Resources for Investigators and Study Chairs

What is NCORP?

The NCI Community Oncology Research Program (NCORP) is a national network of investigators, cancer care providers, academic institutions, and other organizations. The NCORP Network is comprised of two main entities NCORP Community Affiliates and NCORP Research Bases. 

University of Rochester Cancer Center (URCC) NCORP Research Base:  The URCC NCORP Research Base (previously named the URCC CCOP Research Base) was the first NCI-funded Research Base housed within a cancer center in the country.  The URCC Research Base has been funded continuously since 1983 and has focused exclusively on cancer control for the past 25 years.  In an effort to provide cancer patients who choose to receive their treatments in smaller community-based oncology practices rather than large academic cancer centers the opportunity to participate in cutting-edge cancer clinical trials, the NCI developed the NCORP research network.  The purpose was to involve community physicians in clinical research and make state-of-the-art treatment and cancer control research available to patients of community physicians. 

NCORP Community Affiliates are groups of private practice physicians (medical oncologists, radiation oncologists, pediatric oncologists), and ancillary staff, such as clinical research coordinators, data managers, nurses, social workers and other support personnel, who are paid by the NCI for infrastructure costs and each patient accrual related to enrolling participants on and completing large multicenter phase III studies designed and conducted by Research Bases.  NCORP Affiliates are paid to enter patients on both national treatment trials and cancer control trials.  There are 46 NCORP Affiliates throughout the United States.  Nineteen of them are associated with the URCC NCORP Research Base. 

Research Bases are hubs that design and conduct the NCORP multi-center cancer prevention, control, screening and post-treatment surveillance clinical trials and cancer care delivery research (CCDR) studies.  Research Bases consist of researchers with comprehensive expertise in cancer clinical trials.  The bases are funded by the NCI to provide the established infrastructure including: administration, data management, scientific and statistical leadership, study operational processes and personnel, and regulatory compliance for clinical trials and cancer care delivery research.  There are currently 7 NCORP Research Bases.  Other research activities involve onsite auditing and the assurance of regulatory procedures.  The URCC NCORP Research Base has successfully completed numerous, large (N ranging from 300 to 1500), multicenter phase III randomized clinical trials in the area of side-effect management and cancer control.  (See listing of recent studies below)   

Each NCORP affiliate has designated research staff including medical oncologists, clinical research coordinators, data managers, and others who are dedicated to and experienced in conducting multicenter phase III RCTs with NCI Research Bases.  The Research Base holds an annual meeting to launch new studies and review ongoing RCTs that NCORP Affiliate PIs and staff are required to attend.  The Research Base also manages a secure website to provide NCORPs with study materials (e.g., protocols, consent forms, data collection forms, amendments, announcements, operations manuals, etc.) and performs regular onsite audits at NCORP Affiliate sites according to specification set forth by the NCI Clinical Trials Monitoring Branch.  The Research Base also has a dedicated staff of over 65 members that is responsible for ensuring the successful completion of trials. 

The listings below are current or recently completed URCC NCORP Research Base cancer control protocols within our multi-institutional network:

  • Prevention of Delayed Nausea: A Phase III Double-Blind Placebo-Controlled Clinical Trial
  • Phase III Randomized, Placebo-Controlled, Double-Blind Trial of the Effect of Modafinil on Fatigue in Cancer Patients Receiving Chemotherapy
  • Dyspnea in Cancer Patients
  • A Phase II/III Randomized, Controlled Clinical Trial of Giner (Zingiber Officinale) for Nausea Caused by Chemotherapy for Cancer
  • Phase III Trials of Naproxen for Bone Pain
  • Phase II/III Trial of Yoga for Persistent Sleep Dermatitis
  • Phase III Trial of Curcumin for Radiation Dermatitis
  • Phase III Trial of Excercise for Cancer-Related Fatigue
  • Congnitive Impairments in Breast Cancer and Lymphoma Patients 


folder icon 0 Resources for Writing Concepts and Protocols
If you are looking for help or resources with you project please fill out the Resource Request Form above and someone from our unit will review your request. Once reviewed you will be contacted by one of our investigators. Some examples of resources that we can offer are: 
  • Concept examples and templates
  • Consent and Protocol examples and templates 
  • Grant writing examples and templates
Please note that you need to fill out the Resource Request Form to contact us about resources.


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